I generally use W = qΔV to solve for work.
ΔV is in units of Volts or J/C, so the second equation (ΔV = Ed) cannot by itself get you a measure of work (Joules).
As far as comparing E/M work to gravitational work, you have in both equations some fixed point of given charge or mass, distance between the two points (one fixed and one mobile), some displaced point of given charge or mass, and a constant, so the equations are in some sense comparable.
Work is the integral of force with respect to r, so for the gravitational case, you get W = -GM1M2/r, and for the E/M case, you get W = -kq1q2/r, with r evaluated from some start point A and some end point B.
Simplified, for gravitational work, W = mgh via substituting in g, and for E/M work, W = qΔV via substituting in ΔV. So in terms of the second paragraph, where the charge is the quality of a given particle affected by an E/M field, and mass is the quality of a given particle affected by a gravitational field, ΔV can be thought of as the E/M equivalent to (gh). In other words, as (g*h) tells you the per kg change in gravitational potential energy between two points, ΔV tells you the per coulomb change in E/M energy between two points. For both cases, change in energy is work.
Looking at the variables underlying g*h versus ΔV, it may be easier to see that they basically act equivalently. g is related to the mass of the fixed object (usually the Earth), radius of the fixed object (Earth), and the constant G. As for most MCAT problems, we have a fixed radius and mass, g is constant, so in g*h, h or Δr is the only variable. ΔV is based off the charge of the fixed object, the "radius" or distance from the fixed object to the second object at point A, the distance from the fixed object to the second object at point B, and the constant k. As the closest thing the MCAT can get to gravity's "default" of the Earth is maybe a proton or electron's elementary charge, you will often have 2 or 3 variables that can affect ΔV, though as you stated, you may just be given ΔV in the question itself.
So in summary, E/M's Voltage to Electrical potential energy is akin to gravity's (g*h) to Gravitational potential energy.