I assume you are interested in combining a basic science career with clinical practice in the inpatient setting. My response to you is that it depends on the stage in your career.
I attend on inpatient cardiology services 4 weeks a year, with other minimal commitments (occasional weekend call, specialized clinic and miscellaneous stuff). Overall, I was able to negotiate an 80% effort for research and 20% effort for clinical. That being said, I have my own NIH grant and my pay is primarily for my research (my compensation for clinical duties is pretty minimal). Generally, the convention for early/junior faculty physician-scientists is to keep research commitment to >=75% (primarily because it is mandated by the NIH K08 and K99 mechanisms and BWF CAMS). It is definitely hard to get anything accomplished on less than that, especially in these ultra-competitive funding times (which is predicted to get worse before it gets any better).
If you are not yet in the position to seek out faculty positions, and if you are only getting started with research, then I have to give you some tough love here. Basic science is hard. People will have their own opinions about this, but most people who have gone the distance with both medicine and lab research will say that science is infinitely harder (with a greater measure of luck and uncertainty). Succeeding in these times require you to give 110%. If you have completed clinical training with little prior research experience, you will need to spend dedicated research time for several years and crank out papers on a postdoc salary (with occasional clinical moonlighting to pay the bills). It is doubtful you will make 100K on this schedule and getting anything substantive accomplished. If you have student loans, be sure to choose a line of research that is PATIENT ORIENTED CLINICAL RESEARCH, so that you can qualify for NIH LRP (Loan Repayment Program). NIH LRP does NOT fundamentally support basic research. Be sure to visit the NIH LRP web site to review your qualifications and make sure your research falls wtihin eligibility. Once you've completed a successful postdoc (defined by high impact publication/s and competitiveness for independent grant funding), THEN you can be in the position to negotiate a faculty appointment with a research and clinical effort split.
Good luck!