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- Apr 1, 2013
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There are 5 docs in my town, the main one I go to is an older guy, hes very knowledgeable and knows what hes doing. Its rare that I'll suggest a drug to him and he won't know what it is (although he often doesn't know the pharmacology behind it). But when I talk to him about things like nutrition and nootropics hes completely clueless. I told him about acetylcarnitine being a mitochondrial antioxidant and he'd never even heard of it. I don't him about nootropics like piracetam, vinpocetine and DMAE and he hadn't heard of any of them. There are probably doctors around that are into this stuff but I haven't met any yet. I'm guessing its not part of the med school curriculum which is ridiculous. For years I had a problem with lethargy and I felt like I needed meds to balance some kind of neurotransmitter imbalance. The meds worked to a degree but later down the line I found out I'm gluten intolerant and if I avoid eating gluten, the lethargy goes away. It was a herbalist that told me about food intolerances. The only help the docs could give me was prescribing me meds I specifically asked for (sometimes it would be a battle to get them to prescribe me something for an off label use).
And as for nootropics, theres fairly well established scientific theory behind how and why they work. DMAE for example gets binded to phospholipids (in place of choline) and gets incorporated into neuron membranes where it acts as an antioxidant. All docs should know that because of its implications for treating dementia. Coenzyme-Q10 and acetylcarnitine act as antioxidants in the place where they are most needed, the mitochondria, I'm amazed docs don't recommend old people take these supplements. Ampakines are positive allosteric modulators of the AMPA receptor which enhance learning and memory abilities. They have neuroprotective properties, I can't remember the mechanism behind that though. Vinpocetine increases cerebral blood flow and counteracts ischemia in the brain.
I think the medical system needs to be revamped. Way too much responsibility is put on doctors, they have to have an extremely wide range of knowledge, and since they're only human theres only so much they have the time to learn. I think the position of GP should be split into about 3 different fields, so they can specialise better. Psychiatry should also be split into two or more fields and nutrition, nootropics, alternative medical practices (which have been proven effective) should be incorporated into mainstream medicine. For example there should be psychiatrists who specialise in repairing and enhancing brain activity (as opposed to all round psychiatrists who often just prescribe meds to cover the symptoms without treating their cause). For example, a psychiatrist that is well versed in nutrition, nootropics as well as various drugs that target the CNS, but in this case his expertise is not in using drugs to relieve symptoms, but more to allow the brain to mend itself more effectively. I can't think of a specific example of that right now, but kinda like the way taking H2 antagonists allows stomach ulcers to heal.
I'm not a med student, so some of what I said there about how the system works is probably wrong, no need to flame me for that, just point out the mistakes. Chemistry and pharmacology are my fields, so I'm interested in medicine, but I'm not a big fan of the medical establishment itself (or the establishments I have to deal with in my field for that matter). We need to put the regulatory bodies back in their place. Their place is QA. Not legislation. In my country they made melotonin and gingko biloba prescription only. I'm fairly sure nobody would approve of that decision if they knew about these substances, but this regulatory body just goes ahead and makes these decisions for us whether we agree or not. Melotonin is a hormone released by the pineal gland when there is a lack of light hitting the retina. It readily crosses the blood brain barrier making it a good, safe sleep aid. It also happens to be a powerful antioxidant so has the added benefit of protecting neurons. It also counteracts adrenergic related tachycardia and hypertension. Thanks to the IMB (the Irish version of the FDA), the only way to obtain melotonin here is to get a prescription from a doctor, and pay a hefty fee (€40 for 30 2mg tablets) and its not covered by health insurance. In America I can get 100 10mg tablets for about $20. Sure, they're not bound by the same strict quality control guidelines but since they're not in the business of injuring people, its in their interest of supplement manufacturers to have a competent QC team on board.
I want to see the system change radically, but for that to happen we all need to work together to get it changed, because the government only makes the changes we demand when they can no longer ignore the demands like they do when its just a small group of people making them.
And as for nootropics, theres fairly well established scientific theory behind how and why they work. DMAE for example gets binded to phospholipids (in place of choline) and gets incorporated into neuron membranes where it acts as an antioxidant. All docs should know that because of its implications for treating dementia. Coenzyme-Q10 and acetylcarnitine act as antioxidants in the place where they are most needed, the mitochondria, I'm amazed docs don't recommend old people take these supplements. Ampakines are positive allosteric modulators of the AMPA receptor which enhance learning and memory abilities. They have neuroprotective properties, I can't remember the mechanism behind that though. Vinpocetine increases cerebral blood flow and counteracts ischemia in the brain.
I think the medical system needs to be revamped. Way too much responsibility is put on doctors, they have to have an extremely wide range of knowledge, and since they're only human theres only so much they have the time to learn. I think the position of GP should be split into about 3 different fields, so they can specialise better. Psychiatry should also be split into two or more fields and nutrition, nootropics, alternative medical practices (which have been proven effective) should be incorporated into mainstream medicine. For example there should be psychiatrists who specialise in repairing and enhancing brain activity (as opposed to all round psychiatrists who often just prescribe meds to cover the symptoms without treating their cause). For example, a psychiatrist that is well versed in nutrition, nootropics as well as various drugs that target the CNS, but in this case his expertise is not in using drugs to relieve symptoms, but more to allow the brain to mend itself more effectively. I can't think of a specific example of that right now, but kinda like the way taking H2 antagonists allows stomach ulcers to heal.
I'm not a med student, so some of what I said there about how the system works is probably wrong, no need to flame me for that, just point out the mistakes. Chemistry and pharmacology are my fields, so I'm interested in medicine, but I'm not a big fan of the medical establishment itself (or the establishments I have to deal with in my field for that matter). We need to put the regulatory bodies back in their place. Their place is QA. Not legislation. In my country they made melotonin and gingko biloba prescription only. I'm fairly sure nobody would approve of that decision if they knew about these substances, but this regulatory body just goes ahead and makes these decisions for us whether we agree or not. Melotonin is a hormone released by the pineal gland when there is a lack of light hitting the retina. It readily crosses the blood brain barrier making it a good, safe sleep aid. It also happens to be a powerful antioxidant so has the added benefit of protecting neurons. It also counteracts adrenergic related tachycardia and hypertension. Thanks to the IMB (the Irish version of the FDA), the only way to obtain melotonin here is to get a prescription from a doctor, and pay a hefty fee (€40 for 30 2mg tablets) and its not covered by health insurance. In America I can get 100 10mg tablets for about $20. Sure, they're not bound by the same strict quality control guidelines but since they're not in the business of injuring people, its in their interest of supplement manufacturers to have a competent QC team on board.
I want to see the system change radically, but for that to happen we all need to work together to get it changed, because the government only makes the changes we demand when they can no longer ignore the demands like they do when its just a small group of people making them.