Why does mineral oil lead to steatorrhea?

[whatdidigetinto]

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I know it is a laxative, but what's the reason?
''Mineral oil is an emollient laxative. It acts by ******ing intestinal absorption of fecal water, thereby softening the stool." Now fat soluble vitamins wont be affected by the latter obviously because they arent water soluble, so again i ask why does mineral oil negatively affect the absorption of fat soluble vitamins?😕

 

[Phloston]

I know it is a laxative, but what's the reason?
''Mineral oil is an emollient laxative. It acts by ******ing intestinal absorption of fecal water, thereby softening the stool." Now fat soluble vitamins wont be affected by the latter obviously because they arent water soluble, so again i ask why does mineral oil negatively affect the absorption of fat soluble vitamins?😕

Considering mineral oil would not be absorbed, it must decrease absorption of fat-soluble vitamins, because it would force excretion of them.

But yeah, it's a stool softener.

Btw, I had also seen a practice question asking about the MOA of docusate. It acts as a detergent, thereby allowing water and fatty substances to mix.

 

[alternatego]

Considering mineral oil would not be absorbed, it must decrease absorption of fat-soluble vitamins, because it would force excretion of them.

But yeah, it's a stool softener.

Btw, I had also seen a practice question asking about the MOA of docusate. It acts as a detergent, thereby allowing water and fatty substances to mix.

That question was in Qbank, right?

 

[Myxedema]

I think it goes like this: Mineral oil coats what is inside the intestinal lumen. Fat needs to be emulsified by bile salts for absorption, but since it becomes coated by this oil, it is excreted instead. Also, mineral oil, as its name implies, is fat as well so it may interfere with the tests used for detecting steatorrhea.

 

[Phloston]

That question was in Qbank, right?

I think it may have been in GT QBank. I can't recall 100% where.

 

[whatdidigetinto]

Thanks guys