SDN Members don't see this ad. (About Ads) I was recently moonlighting a saw a woman with schizophrenia, alcohol dependence (+ h/o complex withdrawal), hepatitis who presented to the ED acutely psychotic. She denied any recent alcohol or other drug use. On my clinical exam, I did NOT see signs of intoxication. Her clinical presentation was highly consistent with acute exacerbation of schizophrenia rather than substance use or delirium - but that's only so good. I wanted to get labs to make sure there was a cause for delirium (he has been delirious from opioids/pancreatitis before). However, the patient refused labs at all. Would you restrain this woman to get labs? If not, what would your next step be?