Hey man. I'd be wary of advice from strangers on the internet. If at all possible, please find someone you trust, and who has relevant experience to talk to about this. Dude, this is serious business.
So ironically, here's my advice.
I've been in exactly the same situation as you, except that it was my wife choosing med schools and me paying the bills. We even started in NorCal. My family is from the East Coast.
My wife and I discussed EVERYTHING in advance, and made a plan for every school she wound up applying to, on either coast. The value of the med school HAD TO be worth he sacrifice of living apart, or of me disrupting my career and finding a new job. Otherwise, it's wasn't worth applying to.
We wound up doing LDR for two years, and needed a dose of luck to get out of that situation.
There's only one question here: What does your wife think?
It doesn't really matter what anyone else thinks. You and your wife have to agree on the plan, and how to share the sacrifices -- LDR, she follows you around, whatever.
Ideally, you should have discussed this ahead of time and create a rank list of sorts. You should not have applied to programs if you and your wife couldn't agree on a plan on how to allow you to attend. REMEMBER THIS before you rank for residency.
In fact, you WILL have to go through this again for residency, and possibly for fellowship. My wife and I have done both, and we went over every detail of both rank lists in advance.
Med school and residency is going to be at least 7 years. Could be 12 years or more (e.g., med school, GS residency, required research, fellowship) You and your wife really need to plan this out. Maybe Einstein's reputations so much better than TUCOM that it might be worth it to increase your competitiveness for residency later, so you can move back to be with your wife.... although California is always competitive because everyone* wants to move there.
*hyperbole, of course
The good news: if you and your wife agree that marriage is "til death do us part", all your shared sacrifice is an investment. An investment in your career is an investment in your life together.
Talk to your wife. Both of you should know: it is a HUGE upfront cost: time, money, lifestyle, the separation.
Try to wrap your mind around that. Once you do: it's even bigger than that. Repeat.
And even after all that, your marriage might not survive the strain. You hope it will, but you don't know.
Shouldn't acceptance deadline be like this week? Seriously dude, good luck. I feel for you.