anomerization vs. mutarotation???

[premd]

Can someone explain to me the difference between anomerization vs. mutarotation? Thanks!!!

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[BloodySurgeon]

I think its the same thing. Anomer refers to the carbon that is attatched to 2 Oxygen atoms or the anomeric carbon. The anomeric carbon can rearrange itself between alpha and beta form if its a reducing sugar (through mutarotation or anomerization), however it usually has a preference of one over the other.

 

[BloodySurgeon]

I could be wrong so a second opinion will be helpful

 

[BerkReviewTeach]

Can someone explain to me the difference between anomerization vs. mutarotation? Thanks!!!

The difference is really subtle. Anomerization (or anomerism) refers to the formation of an anomer from the straight-chain form of the sugar.

Mutarotation in the interconversion between the alpha-anomer and the beta-anomer.

For all intent and purpose, they can be considered synonymous.

The typical example is as follows:

If a pure sample of beta-D-glucopyranose is added to water it initially exhibits a specific rotation of +18.7 degrees. Over time, this number rises until it gradually reaches +52.7 degrees. Given that the alpha anomer has a specific rotation of approximately +112 degrees, what can be said about the ratio of the anomers in solution?

a) Beta is 86% and Alpha is 14%
b) Beta is 64% and Alpha is 36%
c) Beta is 36% and Alpha is 64%
d) Beta is 14% and Alpha is 86%

The question is answered by wieghted averaging, and doesn't require knowing the difference between mutarotation and anomerization, only that it is possible to have the anomers convert into one another.

 

[BloodySurgeon]

the answer is b right?

 

[g8orlife]

the answer is b right?

Yes. ... in case you've spent the last 2 years stressing over this

 

[Jeff85]

How do you get b?

 

[kentavr]

x*18.7 +(1-x)112=52.7 ->
x~0.64