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BIO 107: Human Physiology Laboratory
This laboratory course is inquiry based, so the subject matter of the course will change in successive years. In 2013-14, the question to be researched will be, during exercise (physical work): "Is lactate a cause or consequence of muscle fatigue?" Students must be willing to participate both as experimenter and as subject, and be available for all discussion and lab sessions for the entire quarter. Since many experiments will involve exercise routines, students must be in good physical condition and sign a medical consent form. Prerequisite is Bio 42 or HumBio 4A. Satisfies WIM in biologynnCourse will be offered in Fall 2013 and Spring 2014. Enrollment for each course is limited to 16 students by application.
BIO 108: Essential Statistics for Human Biology (HUMBIO 85A)
Introduction to statistical concepts and methods that are essential to the study of questions in biology, environment, health, epidemiology and related areas. The course will teach and use the computer language R. Topics include distributions, probabilities, likelihood, linear models; illustrations will be based on recent research.
BIO 109B: The Human Genome and Disease: Genetic Diversity and Personalized Medicine (BIO 209B, BIOC 109B, BIOC 209B)
Continuation of 109A/209A. Genetic drift: the path of human predecessors out of Africa to Europe and then either through Asia to Australia or through northern Russia to Alaska down to the W. Coast of the Americas. Support for this idea through the histocompatibility genes and genetic sequences that predispose people to diseases. Guest lectures from academia and pharmaceutical companies. Prerequisite: Biology or Human Biology core. Students with a major, minor or coterm in Biology: 109A/209A or 109B/209B may count toward degree program but not both.
BIO 110: DNA Replication and Genomic Maintenance (BIO 210)
Maintenance of the genome and its accurate replication are prerequisites for life. DNA replication is also intricately connected to pathways for responding to genotoxic stress, which include inevitable collisions with transcription. In eukaryotes, DNA repair and replication are tightly connected to chromatin modification. Emphasis for lecture topics include: DNA-templated chromatin transactions; Chromatin manipulation during replication and DNA damage responses; Structural biology and molecular mechanisms of replication and DNA repair enzymes; Inducible responses to genotoxic stress; Relationships of DNA damage processing to mutagenesis, carcinogenesis, aging and human genetic disease.
BIO 128: Geographic Impacts of Climate Change: Mapping the Stories
Climate change imparts political, socioeconomic and ecological impacts worldwide, creating an urgent need for scientists to communicate with policy-makers. Students will collect data for a region of the US from multiple sources ranging from academic journals to popular media to create an interactive Story Map ( http://storymaps.arcgis.com) that merges the scientific and human dimensions of climate change. Students will present this map to state and national policy-makers. Students enrolled in 3 credits will have an emphasis on engagement of community partners in addition to normal class participation.
BIO 150: Human Behavioral Biology (BIO 250, HUMBIO 160)
Multidisciplinary. How to approach complex normal and abnormal behaviors through biology. How to integrate disciplines including sociobiology, ethology, neuroscience, and endocrinology to examine behaviors such as aggression, sexual behavior, language use, and mental illness.
BIO 177: Plant Microbe Interaction (BIO 277)
Molecular basis of plant symbiosis and pathogenesis. Topics include mechanisms of recognition and signaling between microbes and plant hosts, with examples such as the role of small molecules, secreted peptides, and signal transduction pathways in symbiotic or pathogenic interactions. Readings include landmark papers together with readings in the contemporary literature. Prerequisites: Biology core and two or more upper division courses in genetics, molecular biology, or biochemistry. Recommended: plant genetics or plant biochemistry.
BIO 182: Modeling Cultural Evolution (BIO 282)
Seminar. Quantitative models for the evolution of socially transmitted traits. Rates of change of learned traits in populations and patterns of cultural diversity as a function of innovation and cultural transmission. Learning in constant and changing environments. Possible avenues for gene-culture coevolution.
BIO 107: Human Physiology Laboratory
This laboratory course is inquiry based, so the subject matter of the course will change in successive years. In 2013-14, the question to be researched will be, during exercise (physical work): "Is lactate a cause or consequence of muscle fatigue?" Students must be willing to participate both as experimenter and as subject, and be available for all discussion and lab sessions for the entire quarter. Since many experiments will involve exercise routines, students must be in good physical condition and sign a medical consent form. Prerequisite is Bio 42 or HumBio 4A. Satisfies WIM in biologynnCourse will be offered in Fall 2013 and Spring 2014. Enrollment for each course is limited to 16 students by application.
BIO 108: Essential Statistics for Human Biology (HUMBIO 85A)
Introduction to statistical concepts and methods that are essential to the study of questions in biology, environment, health, epidemiology and related areas. The course will teach and use the computer language R. Topics include distributions, probabilities, likelihood, linear models; illustrations will be based on recent research.
BIO 109B: The Human Genome and Disease: Genetic Diversity and Personalized Medicine (BIO 209B, BIOC 109B, BIOC 209B)
Continuation of 109A/209A. Genetic drift: the path of human predecessors out of Africa to Europe and then either through Asia to Australia or through northern Russia to Alaska down to the W. Coast of the Americas. Support for this idea through the histocompatibility genes and genetic sequences that predispose people to diseases. Guest lectures from academia and pharmaceutical companies. Prerequisite: Biology or Human Biology core. Students with a major, minor or coterm in Biology: 109A/209A or 109B/209B may count toward degree program but not both.
BIO 110: DNA Replication and Genomic Maintenance (BIO 210)
Maintenance of the genome and its accurate replication are prerequisites for life. DNA replication is also intricately connected to pathways for responding to genotoxic stress, which include inevitable collisions with transcription. In eukaryotes, DNA repair and replication are tightly connected to chromatin modification. Emphasis for lecture topics include: DNA-templated chromatin transactions; Chromatin manipulation during replication and DNA damage responses; Structural biology and molecular mechanisms of replication and DNA repair enzymes; Inducible responses to genotoxic stress; Relationships of DNA damage processing to mutagenesis, carcinogenesis, aging and human genetic disease.
BIO 128: Geographic Impacts of Climate Change: Mapping the Stories
Climate change imparts political, socioeconomic and ecological impacts worldwide, creating an urgent need for scientists to communicate with policy-makers. Students will collect data for a region of the US from multiple sources ranging from academic journals to popular media to create an interactive Story Map ( http://storymaps.arcgis.com) that merges the scientific and human dimensions of climate change. Students will present this map to state and national policy-makers. Students enrolled in 3 credits will have an emphasis on engagement of community partners in addition to normal class participation.
BIO 150: Human Behavioral Biology (BIO 250, HUMBIO 160)
Multidisciplinary. How to approach complex normal and abnormal behaviors through biology. How to integrate disciplines including sociobiology, ethology, neuroscience, and endocrinology to examine behaviors such as aggression, sexual behavior, language use, and mental illness.
BIO 177: Plant Microbe Interaction (BIO 277)
Molecular basis of plant symbiosis and pathogenesis. Topics include mechanisms of recognition and signaling between microbes and plant hosts, with examples such as the role of small molecules, secreted peptides, and signal transduction pathways in symbiotic or pathogenic interactions. Readings include landmark papers together with readings in the contemporary literature. Prerequisites: Biology core and two or more upper division courses in genetics, molecular biology, or biochemistry. Recommended: plant genetics or plant biochemistry.
BIO 182: Modeling Cultural Evolution (BIO 282)
Seminar. Quantitative models for the evolution of socially transmitted traits. Rates of change of learned traits in populations and patterns of cultural diversity as a function of innovation and cultural transmission. Learning in constant and changing environments. Possible avenues for gene-culture coevolution.
