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http://www.forbes.com/sites/matthew...the-story-of-a-dangerous-opioid/#3752da46ff03
"At Sciele he’d become fascinated by another of its products: a spray form of nitroglycerin used by heart patients to stop attacks of chest pain. “Patients loved it,” Kapoor says. “I started looking into the sprays, and to my surprise, I found it was the only product that was sold as a spray in this country.” What other drug would work well as a spray? Well, fentanyl, which cancer patients needed for rapid relief of pain. The idea wasn’t a fit for Sciele, so Kapoor brought it to Insys, a small company he’d founded in 2002. Fourteau joined the board in 2011, and Insys decided on a sales-force strategy much like Sciele’s, with young, aggressive salespeople. Asking them to sell a potentially deadly narcotic on an incentive plan created a powder keg primed to explode."
"At Sciele he’d become fascinated by another of its products: a spray form of nitroglycerin used by heart patients to stop attacks of chest pain. “Patients loved it,” Kapoor says. “I started looking into the sprays, and to my surprise, I found it was the only product that was sold as a spray in this country.” What other drug would work well as a spray? Well, fentanyl, which cancer patients needed for rapid relief of pain. The idea wasn’t a fit for Sciele, so Kapoor brought it to Insys, a small company he’d founded in 2002. Fourteau joined the board in 2011, and Insys decided on a sales-force strategy much like Sciele’s, with young, aggressive salespeople. Asking them to sell a potentially deadly narcotic on an incentive plan created a powder keg primed to explode."