And here i am, the OP, ready to respond to everyone. Thank you for all your advice. I contacted one DO program, NYCOM, and Drexel. I got a return phone call from admissions and both said the following. ---- If you take all of your prereqs at community college, that will not be frowned upon, as we understand that sometimes for financial reasons, student cannot continue to take all of their courses at their home school. That being said, we do encourage you to take your prereqs at your 4 years school as the course material might be a bit more challenging, but again, it is your prereqs and it is best you complete them where is most convinient for you. We look forward to reviewing your application. ----- So, what do you guys think of that?