Efficient way to solve genetics mcat questions?

This forum made possible through the generous support of SDN members, donors, and sponsors. Thank you.

The_Juggernaut

New Member
15+ Year Member
Joined
Jun 6, 2007
Messages
8
Reaction score
1
For example if the question is all factor 8 gene mutations result in hemophilia, which of the following choices is false? (This is how I summarized the question).
Given the following info: hemophilia is a sex-linked disease, recessive, located on x-chromosome.
Answer choices are something like this and A & C are correct.

A. hemophiliac mothers have healthy sons
B.Healthy fathers have Hemophiliac sons
C.Healthy fathers have Hemophiliac daughters
D.hemophiliac fathers have healthy sons

Members don't see this ad.
 
It might be helpful if you took a screen shot or smartphone image of the exact question and answer choices. You have likely missed something in the wording. For what it is worth:

A - Hemophiliac mothers have two X chromosomes with the mutation of interest if the disease is x-linked recessive. A father never contributes an "X" chromosome to his son (only a y); thus, a hemophiliac mother would be the only contributor of an X chromosome to her son, which would be diseased. All sons of a hemophiliac mother should have the mutation, and thus the disease.
B - You're being too vague. Yes, it is possible for some healthy fathers to have diseased sons as it depends entirely on the mother.
C - Healthy fathers will never have hemophiliac daughters if the disease is x-linked recessive.
D - Same as B - entirely based on mom.

Choice A will never happen (all sons get mutant X allele). Choice C will never happen (all daughters get normal X allele).
 
Top