An untreated newborn diagnosed with classical galactosemia is expected to have an accumulation of which of the following substances in the blood?
A. galactose only
B. galactose-1-phosphate only
C. both galactose and galactose-1-phosphate
D. neither galactose nor galactose-1-phosphate
The answer listed is C. However, the passage states that classical galactosemia has a defective galactokinase protein. How can there be an accumulation of galactose-1-phosphate is the enzyme leading to this product is defective? The answer key does not really address this. Am I simply overthinking this?
A. galactose only
B. galactose-1-phosphate only
C. both galactose and galactose-1-phosphate
D. neither galactose nor galactose-1-phosphate
The answer listed is C. However, the passage states that classical galactosemia has a defective galactokinase protein. How can there be an accumulation of galactose-1-phosphate is the enzyme leading to this product is defective? The answer key does not really address this. Am I simply overthinking this?