I've always been taught that as long as you ID the sample as plasma/interpret with the proper reference intervals or at least recognize the artifact, you're fine, because it's not that it's creating 'abnormal' results so much as people still use serum normals to interpret plasma.
@JaynaAli do you have any opinions on this? I mean obviously do the serum if you can because it's easier to interpret quickly since that's what everyone is used to, but I've had a clin pathologist say plasma chems are fine as long as you interpret accordingly, and that it's mostly just potassium and protein that are reliably going to be different than serum in most analyzers.
Out of curiosity, I skimmed a few papers on the subject and people seem to be pretty 50/50 as to whether or not the differences are statistically significant, and most of the papers I read (just the abstract tbh) said the differences weren't medically significant. I'm not saying we should all start running plasma chems or anything, I've just been taught that it's an option that can come in handy if for some reason you can't get more blood. Maybe I've been taught horribly wrong, idk.