Presumably you've already made 3 years of low payments under some program, but you haven't told us what it is. Nor is there enough detail to answer your question.
If you're going for PSLF, you want to stay in a government program and you want to minimize your payments. You also want to be savings up a side fund, just in case.
You probably want to be in PAYE as an attending (since REPAYE doesn't put a cap on payments at the regular 10 year payment). I wouldn't think MFS as an attending is going to help any given a lower earning spouse. However, REPAYE with MFS was probably the right move as a resident, but that's water under the bridge now.
But this is a situation where you really need to run the numbers. Probably worth paying a pro a couple hundred bucks to help you run them.
Actually, I'm not clear if you're a graduating med student or a graduating resident. I was assuming resident as this is a resident forum. But you're probably a med stud per your avatar. Still worth paying for advice, but the answer for you is probably REPAYE + MFS.