NBME Question - Alzheimer's??

[The Anhedonia]

A 58-year-old woman dies after a 2-year history of progressive memory loss, disorientation to time and place, and increasmgly frecuent episodes of lethargy and confusion.
There were no focal neurologic deficits. Which of the following findings is most likely at autopsy?

A) Decreased concentration of v-aminobutync aod (GABA) "'the stnatum and the substantia nigra
B) Degeneration of cortical and basal forebrain neurons
C) Formation of Lewy bodies "' the pars compacta of the substantia mgra
D) Increased concentration of acetylcholinesterase in the cerebral cortex
E) Presence of antibodies lo the nicotinic cholinergic receptor

thanks yall

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[RedSoxSuck]

A 58-year-old woman dies after a 2-year history of progressive memory loss, disorientation to time and place, and increasmgly frecuent episodes of lethargy and confusion.
There were no focal neurologic deficits. Which of the following findings is most likely at autopsy?

A) Decreased concentration of v-aminobutync aod (GABA) "'the stnatum and the substantia nigra
B) Degeneration of cortical and basal forebrain neurons
C) Formation of Lewy bodies "' the pars compacta of the substantia mgra
D) Increased concentration of acetylcholinesterase in the cerebral cortex
E) Presence of antibodies lo the nicotinic cholinergic receptor

thanks yall

I think its B. Its in either nbme 12 or 11. You should check out those threads.

 

[The Anhedonia]

I think its B. Its in either nbme 12 or 11. You should check out those threads.

from NBME 5 actually

 

[Belleza156]

from NBME 5 actually

Thanks for that! I couldn't figure out why I didn't remember this question...done both 11&12, but not 5.

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