New Yorker: fMRI and Pain

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drusso

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The Neuroscience of Pain


"Tracey has been looking at pleasure for almost as long as she’s been studying pain. “They are two sides of the same coin,” she told me. Many signs of their interrelation crop up in her work. Chronic-pain patients typically also suffer from anhedonia—the inability to experience pleasure—and research suggests that their brains’ reward systems are wired slightly differently from those in other brains."

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Abusing drugs has a negative effect on a normally pleasurable stimulus creating pleasure thus leading to anhedonia in a iatrogenic manner.
 
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