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PaO2: Temperature Correction

Discussion in 'ITE Keywords' started by excalibur, Nov 21, 2008.

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  1. excalibur

    excalibur Member

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    I couldn't find a really good article explaining this, but from what I could gather it seems that...

    Hyperthermia decreases the solubility of O2 in blood, and therefore increases the PaO2

    Hypothermia increases the solubility of O2 in blood, and therefore decreases the PaO2

    It appears that although these concepts are true, it is unnecessary to make corrections in the PaO2's of ABG's in hypo/hyperthermic pts.

    Does this accurately sum up this keyword? Any additional info or links to good articles would be appreciated.
  2. Freibi

    Freibi

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    http://images.google.de/imgres?imgurl=http://upload.wikimedia.org/wikipedia/commons/8/8a/Oxyhaemoglobin_dissociation_curve.png&imgrefurl=http://reference.findtarget.com/search/oxygen-hemoglobin%2520dissociation%2520curve/&usg=__KVlPmcnA1O8Myhom-o7BjPPl2dg=&h=413&w=439&sz=40&hl=de&start=30&tbnid=rPVgeY-jIn1gUM:&tbnh=119&tbnw=127&prev=/images%3Fq%3Dhemoglobin%2Bbinding%2Bcurve%26start%3D20%26gbv%3D2%26ndsp%3D20%26hl%3Dde%26sa%3DN

    Snow White's mother, the late good queen, lost a drop of capillary blood in the snow while doing her stitchwork, and it looked red (not purple) - this proves the enhanced binding of O2 to hemoglobin in cold temperatures ;)

    So, does anyone know how much it matters within the range of possible body temperatures?
  3. proman

    proman Member Moderator

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    Faust page 22 Blood Gas Temperature Correction has a nice, short description. It's related to pH-stat or alpha-stat management of blood gases while hypothermic (on bypass). The pH and PaCO2 temp difference seems most important. Clinically I don't think the effect of temp on PaO2 is important (other than to know the concept).

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