You do any prone brain tumor resections in pins? I blow off nearly all my agent towards the end of the case prone, give a bit of propofol that is left over from induction so the patient doesn't buck while we flip and the pins are still on.
By then time we flip and the pins are out I have a spontaneously ventilating patient with almost no inhaled agent on board. They can be pretty darn responsive after my bolus wears off and that is exactly what you want after a crani. At the very least, respiratory mechanics tend to be excellent shortly after the flip.
What do you do? Wait 'till you flip to start blowing off the agent, run a remi or precedex drip, use the force?
Listen, amateurs, it's not the drug you use, it's how you use it. To be so closed minded as to other ways to do anesthesia out of your little box is just being blind.