Hey guys, here's my question!
If you have a transmembrane protein that contains basic amino acids on the extracellular side of the cell at pH 7, will the transmembrane be more likely to attract negatively charged particles and vice versa for acidic amino acids?
My thinking was that at a pH of 7 the basic amino acids would be positively charged (protonated) and would have a stronger affinity for negatively charged particles outside the cell. Is this right thinking or do I have this completely wrong?
THANKS
If you have a transmembrane protein that contains basic amino acids on the extracellular side of the cell at pH 7, will the transmembrane be more likely to attract negatively charged particles and vice versa for acidic amino acids?
My thinking was that at a pH of 7 the basic amino acids would be positively charged (protonated) and would have a stronger affinity for negatively charged particles outside the cell. Is this right thinking or do I have this completely wrong?
THANKS