Quinidine. P450 inh or ind?

[medpack87]

Please help! Is quinidine a P450 inhibitor? or a P450 inducer?

I have a 2011 copy of FA where it says it is an inducer. The guys at DIT say so also.

I just saw a FA 2013 copy where it says that quinidine is a P450 INHIBITOR. On p.242.1

which one is it?

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[jwwbear]

Quinidine is a P450 inhibitor. The way I remember this is that quinidine "quiets down" P450.

 

[thawunandonly]

Remember to Google ALWAYS for the most updated Errata of the FA you are using. It is indeed an inhibitor.

 

[medpack87]

Thanks guys