KNOW them cold-- that's where a lot of the biocehm questions are pulled out from, even though they are so rate. I took a short kaplan course, and the biochem dude gave us his top ten list, and he said 7 or 8 usually show up (and this was vouced by my friend who is a M4; he said he looked at the list the morning while eating bfast, and sure enough, 6 of them were on). So, make sure u know those--a lot of them u can figure out the sx based on where the defect is.
Also, only pompe's has CARDIAC effects (cariomegaly), tay sacchs does not have hepatomegaly, while the other lysosomals do. Von gierkes has SEVERE hypoglycemia, becuse it inhibits glc 6 phosphatase, thus, u block the common final p/w for both gluconeogenesis and glycoenolysis. While, Her's disease is deficient in heaptic glycogen phosphorylase, and thus, gluconeo can still take place, and u get mild hypogylcemia and mild liver path. Anyways, u can kinda figure these out--they're not that bad, but then again, i like biochem for some odd reason.
