I graduated recently with a Bio degree in TX. I'll spare everyone the sob story and details--other than stats.
cGPA: 2.6
sGPA: 2.4
MCAT: 522 (took it May)
ECs: 1 publication, plenty of shadowing and clinical volunteer hours.
Most of my pre-reqs were Cs, (F in orgo1, retook for a C, D in Bio2...