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1. Preop evaluation reveals chronic occlusion of lower limb veins and edema - How to manage preop?
I thought we would give therapeutic dose of...
As I understand it:
Heparin binds Platelet factor 4 (PF4)
Heparin-PF4 complex is immunogenic, and causes IgG directed against it
Guys, can anyone please explain me why in heparin induced thrombocytopenia thrombosis occurs?