1. sahell

    NBME Surgery Form 1 questions

    1. Preop evaluation reveals chronic occlusion of lower limb veins and edema - How to manage preop? I thought we would give therapeutic dose of Hep for DVT, which was wrong. Would be give low dose hep prophylaxis? 2. Patient is put on a ventillator probably because of ARDS - Tidal vol 1000ml...
  2. HereWeGo21

    Heparin-induced thrombocytopenia mechanism

    As I understand it: Heparin binds Platelet factor 4 (PF4) Heparin-PF4 complex is immunogenic, and causes IgG directed against it Heparin-PF4-IgG complex binds platelets via their Fc receptors. This causes activation of the platelets Platelet activation and thrombosis. However, this seems...
  3. EmetyreUSMLEStep1Tutor1


    Guys, can anyone please explain me why in heparin induced thrombocytopenia thrombosis occurs?