immunosuppresssion

Hello everyone! I'm a 22-year-old university student from Europe. I'm currently in my 3rd year of studies in a 6-year MD program. According to a serological test (specifically my anti-CCP was 123), it's likely that I'll be diagnosed with rheumatoid arthritis in the foreseeable future. I know...

MMF, Cyclosporine, Prednisolone, Tacrolimus the dose of whatever immunosuppressant used is reduced in around 6 months - 1 year after the transplant. What is the rationale behind this? Wouldn't any allograft, howsoever old, still remain foreign? Does the body learn to consider the graft self...