1,4-electrophilic addition, opposed to 1,2 (what if)

[pineappletree]

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Normally for 1,3-butadienes, a 1,4 is supposed to be more thermodynamically favored as it results in an internal double bond opposed to one at the end.


However, I was wondering if this can be applied to, let's say, a 5,6-decadiene. Would a 1,4 addition still be favored over a 1,2?? (in the context of a MCAT question)

 

[futuredoc4432]

Normally for 1,3-butadienes, a 1,4 is supposed to be more thermodynamically favored as it results in an internal double bond opposed to one at the end.


However, I was wondering if this can be applied to, let's say, a 5,6-decadiene. Would a 1,4 addition still be favored over a 1,2?? (in the context of a MCAT question)

the more substituted double bond is thermodynamically favored, it may not always be the kinetic product though, high heat and time usually lead to thermo product.

 

[loveoforganic]

There's a factor to account for here (other than total substitution of alkenes). That would be breaking up conjugation (1,4) vs not (1,2). If I had to guess, I'd say 1,2 would be thermo and kinetic, but it's really just a guess. Don't think you'd be expected to knowl