2016 HY topics trends

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zeevee

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Hi there ,
people who have already taken the exam this year can you share what new topics are trending in the exam .I know from last year that urinary incontinence and cytochrome enzymes made into the exam big time although both were not covered in FA .

Similarly any new topics which are not thorough in FA or skipped altogether ?
I know discussing topics is not against any policy .
Ebola virus questions ?
Zika virus questions ?

Thanks
 
UWorld updates with about 5-10 new questions every 2 weeks. You can deduce the "trend" of the exam from those questions if you wish. All the stuff you have mentioned above is like 1-2 questions on the exam. Your better off focusing on the meat and potatoes of the exam which is everything in your reading source, where you will get more questions asked.
 
.I know from last year that urinary incontinence and cytochrome enzymes made into the exam big time although both were not covered in FA .
Also p450 and urinary continence are really classic practice questions, that's not something that's new on the exam.
 
Thanks .
Looking for fringe topics .Detailed urinary incontinence questions are part of the new additions in UW.Asking for specific P450 type and number is not very classic I believe .
Let me know what else you think is classically tested .
 
Asking for specific P450 type and number is not very classic I believe .
Yes it is, you need to know p450 inducers (items that increase the rate of liver metabolism and makes any drugs sub-therapeutic) and p450 inhibitors (items that decrease the rate of metabolism and make drugs present in higher concentrations than normal, causing side effects).

p450 inducers are:
"BAG for CPR QTS"
Barbituates, Alcohol, Griseofulvin, Carbemazepine, Phenytoin, Rifampin, Quinidine, Tetracylines, Spironolactone

p450 inhibitors are:
"ID SMACK Quin"
INH, Dapsone, Sulfa drugs, Marcolides, Amiodarone, Cimetidine, Ketoconazole, Quinolones. You can throw Fibrates in there as well.

p450 dependent(drugs that can be affected by p450)
"WEPTD"
Warfarin, Estrogen, Phenytoin, Theophylline, Digoxin

There are a ton of questions that show up where these are the answers.

Let me know what else you think is classically tested .
I am not trying to be mean, but go through a reading source and practice questions, with practice you can come to that conclusion.
 
No , not at all .
I dont think you are being deliberately mean .You dont get my question that is all .The information above is smack in the middle of First Aid .I am pretty solid in mnemonics myself .
Answer this question : Which P450 enzyme metabolizes Warfarin ?
Which P450 enzyme metabolizes morphine ? what is the active metabolite of morphine after it is metabolized ?

With the exception of the names of the drugs these are real exam questions encountered by people .I have read P450 enzyme inhibitors and inducers many times and can vomit out there names quite easily just like you but if in the exam they are asking me the above "fringe" question then I need to know and need to be steered in that direction ahead of time .
I have gone through the central concepts of Step 1 as best as I could . I am looking for guidance to highlight stuff that is tested but missed by me or needs reading and research beyond what is readily available in PUFA and Goljan

P.s : for throwing in Fibrates into your mnemonic you can go like " ID SMACK Quin's GEM " ( Queens have Gems - gem for gemfibrozil ) or " ID SMACK Fabulous Quin" .However , as far as I know quinidine is an inhibitor so the list of drugs is a bit crooked IMO.Also , its a good idea to know the effect of chronic alcoholism vs acute alcohol abuse on P450 .Acute binging is a an inhibitor and out of all the names above I think that concept is key .Cant miss anything that deals with alcohol.
 
Guys as someone who took the step 1 exam in 2015, let me offer some words of advice. I see a lot of students asking one another about topics that are over-represented and/or under-represented on the step 1. Let me tell you that this type of discussion is a waste of time, and will do nothing but cause you stress. You really need to have a good understanding of all topics in the standard MS1-2 curriculum to ensure a strong performance on step 1. As you know there are several resources and question banks that are available, so just prepare thoroughly using them and you will be fine. Yes, you should probably know about incontinence... but not just for step 1, but also for life as a doctor...you should expect to see this problem quite often in patients (especially the elderly).

The step 1 exam that each students receives is generated totally at random, and is generally going to have well-distributed content. In other words, no step 1 exam is going to contain 100 microbiology questions. If any of you read the nbme handbook on how to write a multiple choice test (http://www.nbme.org/pdf/itemwriting_2003/2003iwgwhole.pdf), a big theme they emphasize is that an assessment has to sample the testable knowledge base broadly to be considered good. This is because an exam that is over-represented with certain topics is one that is biased. The objective of the step 1 is to generate a score that is representative of your knowledge, so that if you were to take it multiple times, your performance would be similar. A biased exam with certain topics over-represented would not meet this criteria, and so it would NOT be given to a student on the step 1. Therefore, I am quite certain that every step 1 exam, while it will have some variation in the content presented, will be reasonably broad and comprehensive in its coverage. This was definitely my experience.

That being said, you may hear people say the following:

"dude i had so much anatomy on my test"

"wow they asked me about toxoplasmosis like 100 times"

"i didn't think they could ask so many micro questions in one exam!!!"

"i must have had 10 questions on urinary incontinence"

This is a hypothesis, but what I think happens is that students tend to unintentionally over-represent topics that they get on the exam which they are not 100% confident in. A person who is weak in biochemistry, and then gets 10 biochemistry questions on the exam (which, is only like 3% of a 300+ item test) will think that they got really "slammed" with a bunch of biochemistry. On the other hand, a person who knows their biochemistry cold, would have probably not even noticed these questions.....

In any case, my point is, be wary of people who spout nonsense on what to study and what not to study. You should just know all of the MS1-2 curriculum well (or as much as you can possibly master). Use your review books (first aid, goljan, pathoma etc.) and question banks. Always target your weaknesses and try to minimize them as much as possible. If you learn your medicine well during MS1-2, and prepare diligently for step 1, you will be pleased with your score.
 
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