A funky antibiotic warning...

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tchuptchik

Bonne Vivant Med Student
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1. I posted a question about this earlier tonight and just wanted to make clear I'm not asking for medical advice-- I'm simply intersted what is behind a warning on an antibiotic I've seen...

On Clindamysin "information" it sais that one shouldn't lie down for 30 minutes after taking it. I'm curious if anyone knows what this is a warning for... I thought it sounded a bit wierd (in comparison to the usual take with food or what not).
 
1. I posted a question about this earlier tonight and just wanted to make clear I'm not asking for medical advice-- I'm simply intersted what is behind a warning on an antibiotic I've seen...

On Clindamysin "information" it sais that one shouldn't lie down for 30 minutes after taking it. I'm curious if anyone knows what this is a warning for... I thought it sounded a bit wierd (in comparison to the usual take with food or what not).
Looks like the side effect profile is largely GI issues. Also, it says online somewhere to take with a full glass of water to avoid esophageal irritation. Maybe lying down would risk some sort of reflux-associated upper GI irritation? Just an uneducated guess; what do I know?
 
OP, I PMed you about it a little bit earlier --- it's because certain antibiotics are very abrasive to the esophagus and can cause ulcers. Pills can get "stuck" to the esophagus on their way to the stomach, and remaining upright helps to prevent this problem.
 
OP, I PMed you about it a little bit earlier --- it's because certain antibiotics are very abrasive to the esophagus and can cause ulcers. Pills can get "stuck" to the esophagus on their way to the stomach, and remaining upright helps to prevent this problem.

Bingo, same kinda warning exists with NSAIDs and Fosamax.
 
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