Hello,
I am a little confused on a few world questions that seem contradictory in their explanations. On one question uworld says that with aging, atrophy of myocardium occurs that results in increased interstitial connective tissue, concomitant with extracellular amyloid deposition.
However, in another question where it was discussing hypercalcification of an aortic valve on a normal 75 year old patient, the question asked for what preceded these changes. Uworld answer choice says that in an aging heart valve normal dystrophic calcification occurs and that occurs in the event of cell necrosis. I understand the pathophysiology of that and it makes sense. However, there was also an answer choice that said extracellular amyloid deposition. I figured a normal aging heart valve would have this as well after when i missed the first question. But then the answer explanation said this is only found in amyloidosis.
Can someone help me clear up confusion please
I am a little confused on a few world questions that seem contradictory in their explanations. On one question uworld says that with aging, atrophy of myocardium occurs that results in increased interstitial connective tissue, concomitant with extracellular amyloid deposition.
However, in another question where it was discussing hypercalcification of an aortic valve on a normal 75 year old patient, the question asked for what preceded these changes. Uworld answer choice says that in an aging heart valve normal dystrophic calcification occurs and that occurs in the event of cell necrosis. I understand the pathophysiology of that and it makes sense. However, there was also an answer choice that said extracellular amyloid deposition. I figured a normal aging heart valve would have this as well after when i missed the first question. But then the answer explanation said this is only found in amyloidosis.
Can someone help me clear up confusion please