The rationale for air over saline is you could bounce the plunger so it didn’t get stuck but still had most of the firmness of saline, and avoid pneumocephalus. If you know how to prep the glass syringe that doesn’t happen.
For landmark-based epidurals in the OR or L&D, my personal preference was strongly for the saline-only glass LOR syringe. About 3 mL, and the key was to cover the end of the syringe and apply pressure to drive saline up the side of the plunger and lubricate it. I tried air, and air over saline, but I felt like the compressibility of the air significantly reduced my sensitivity to the loss. Had an attending who personally received a pneumocephalus so she was pretty strongly against using air.
For fluoro-guided, especially with the use of CLO, I don’t think it really matters much. When I started out in practice I was using plastic LOR because the glass was so expensive, then I switched to just 3 mL syringe with contrast because you still get pretty good loss but it’s just a secondary backup to the fluoro.