- Joined
- Sep 6, 2013
- Messages
- 50
- Reaction score
- 0
Can someone explain relationship between calcium and albumin and an easy way to calculate the corrected calcium? i'm lost on this.
Also albumin is negatively charged, hence the attraction between it and calcium.
That member hasn't been seen in 6 years...1. I think that's a myth. "Correction" should be done at any albumin value. A high albumin will obviously elevate the total calcium just as a low albumin does the opposite. Exactly one study had findings that suggested one should not correct total calcium for high albumin, but its findings were never replicated.
2. A bigger problem is that albumin-corrected calcium has been repeatedly shown to be poor at deducing ionized calcium status at any albumin value. Here is a link to a much better--and externally validated--method for deducing ionized calcium status:
qxmd.com/calculate/calculator_704/predicting-ionized-hypocalcemia-in-critical-care