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- Jun 19, 2008
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When you attack a carbonyl (Carboxylic acid, COOH for example) with any given amine (NR3), why will an amide not form if u add in base or acid.
So basically, carbonyl + amine==>amid except when there's acid or base present. Can anyone explain why acid/bases intereferes with this formation?
So basically, carbonyl + amine==>amid except when there's acid or base present. Can anyone explain why acid/bases intereferes with this formation?