Anesthetics general question

Discussion in 'Step I' started by path800, May 17, 2014.

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  1. path800

    path800

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    Does solubility in blood has any relationship with solubility in lipid?
     
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  3. oingoboingo

    oingoboingo boo!

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    This has confused me too. It seems that if something is soluble in lipid, it wouldn't be soluble in blood. But nitrous is insoluble in both (so works fast but has low potency) and halothane is soluble in both (so works slowly but very potent). So I'm going to try not to overthink it, and just memorize that drugs with high blood solubility will work slowly, and drugs with high lipid solubility will be very potent.
     
  4. EazyE1907

    EazyE1907 2+ Year Member

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    Agreed
     
  5. Ismet

    Ismet PGY-fun SDN Administrator 5+ Year Member

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