Annular pancreas and polyhydramnios

[MudPhud20XX]

Can anyone explain the connection between annular pancreas and polyhydramnios? How the heck does annular pancreas lead to polyhydramnios? Many thanks in advance. Below is form Wiki for annular pancreas:

Early signs of abnormality include polyhydramnios (an excess of amniotic fluid), low birth weight, and feeding intolerance immediately after birth.

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[AthenaBC]

Annular pancreas is an embryological deformity in which some of the pancreas surrounds the second part of the duodenum. Normally, the ventral bud of the pancreas should migrate around only the right side of the duodenum to fuse with the dorsal pancreatic bud, but with annular pancreas, the ventral bud splits into two and wraps around both sides of the second part of the duodenum. Sometimes, this is asymptomatic, however, if the pancreatic tissue surrounding this part of the duodenum compresses the duodenum, this can lead to symptoms similar to duodenal atresia because of obstruction of the duodenum, hence the polyhydramnios.

 

[NeuroLAX]

Am I correct in thinking that the polyhydramnios is also due to fetal production of urine (kidneys are OK so they keep contributing to the amniotic fluid buildup, which cannot be swallowed due to the annular pancreas)?

 

[Phloston]

Am I correct in thinking that the polyhydramnios is also due to fetal production of urine (kidneys are OK so they keep contributing to the amniotic fluid buildup, which cannot be swallowed due to the annular pancreas)?

Polyhydramnios would be because either not enough amniotic fluid is swallowed or because too much urine is produced. Maternal diabetes can lead to fetal hyperglycemia (remember that insulin does NOT cross the placenta) and subsequent diuresis.

 

[MudPhud20XX]

So can anyone explain why duodenal atresia is associated with polyhydramnios?

 

[Nephronlearner]

So can anyone explain why duodenal atresia is associated with polyhydramnios?

The foetus swallows the fluid and then the urine created from it leads to formation of 'new fluid' (let's call it... recycling? haha). Thereby smaller lumen in the GI tract (for instance due to annular pancreas) -> impaired swallowing -> more fluid -> polyhydramniosis

 

[dyspareunia]

So can anyone explain why duodenal atresia is associated with polyhydramnios?

Fetus pees just fine with duodenal atresia.

Fetus can't absorb fluid without a functioning GI tract.

Pee (make amniotic fluid) without absorbing (consume amniotic fluid) = polyhydramnios.