Anybody using Andexxa much yet?

[Libertas]

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Curious if anybody has seen many bleeders on Xa inhibitors come through and get andexxa for reversal? $$$$

 

[Shimmy8]

Once that I’m aware of. Some sort of trauma (don’t remember) we were bringing to OR for spine or hip the next day. I saw they got it on arrival, pretty cool! Seemed to work as far as I remember.

 

[CUBR]

Once for a subdural head bleed, and one a for type A dissection patient. Seemed to have worked...well the type A died before she could get on bypass, but it wasn't from bleeding. The nurses were shocked to learn it costs 50K per dose.

 

[Ronin786]

I'll continuously find it interesting that a pharmaceutical company develops an anticoagulant in 2012, then takes 6 years to release the reversal agent. Maybe I'm just ignorant of the drug development process, but it always smelled fishy to me.

 

[AdmiralChz]

Is Andexxxa the dirty stripper sister of Alexa?

 

[Libertas]

I'm liking PTLA as an investment right now. The price has been beaten down a lot recently, but I think usage will make earnings pop soon 🙂

 

[AdmiralChz]

More seriously, our trauma hospital P&T committee rejected a proposal to add it to the formulary. Whatever concoction of PCCs/Blood products brought up was still apparently much less expensive than this stuff from what I’m told.

 

[vector2]

More seriously, our trauma hospital P&T committee rejected a proposal to add it to the formulary. Whatever concoction of PCCs/Blood products brought up was still apparently much less expensive than this stuff from what I’m told.

Do hospitals face any particular liability with a bad outcome if they get get a gomer with a head bleed on pradaxa or xarelto and they don’t carry praxbind or andexxa?

 

[CUBR]

Do hospitals face any particular liability with a bad outcome if they get get a gomer with a head bleed on pradaxa or xarelto and they don’t carry praxbind or andexxa?

They don't seem to. Just send them to some big academic center to take care of the bill.