I majored in physio. At my school, physio is one of the harder majors (as opposed to anatomy, biochem, cell bio, bio, etc) but I truly enjoyed it.
It does make for some potentially awkward interview moments:
Interview: "so you pretty much already took all of the classes in our preclinical curriculum..."
Me: yeah... But there's still a lot I need to learn, especially since our physiology was fairly research intensive
I: I don't think so, I think it's a waste of time for you anyways
Me: uh... I enjoy it?