I applied to six schools (5 US and 1 UK), and most were based on statistics of how likely it was that I get in. I would highly recommend basing where you apply on released statistics. Some people get rejected year after year, and it can be because they applied to statistically very hard schools to get into. Vet school is vet school. Everyone is going to end up with a degree afterward and make themselves an excellent veterinarian if they have the drive, so in my opinion - getting in is the most important thing regardless. Schools post recent class statistics on their websites. They tell you what schools their students went to undergrad at, what their GPA's were, how much experience they had, what their GRE scores were, etc. I looked at those to see which schools I would "fit" to best. I also applied to 1 or 2 long shots, just because you never know! I got interviews at both my long shots, so I guess it didn't hurt!