Ativan XR/loreev

[annoyedpsychiatrist]

Getting a patient on this monday, 1.5mg ativan xr. I only know what ive read, anything useful or interesting about it? Dont see this one too often.

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[littlefred]

Getting a patient on this monday, 1.5mg ativan xr. I only know what ive read, anything useful or interesting about it? Dont see this one too often.

464 dollars even with GoodRx, I suspect insurers won't have it as formulary.

 

[Sushirolls]

This just makes me think of the Dos Equis guy commercials.

'I don't have benzos often, but when I do, its ativan XR'

Meanwhile no reason why not to stick with librium or valium if people want longer half lives.

Depending on half life, maybe, just maybe could see a role in detox facilities for XR to hasten discharge. Tomorrow take this dose. Next day, this dose, and final dose is this on this day.

But I'm not going to waste my time even reading about it to see if has any place/potential - because name brand / on patent / too expensive.

 

[ObsequiousAplomb]

This just makes me think of the Dos Equis guy commercials.

'I don't have benzos often, but when I do, its ativan XR'

Meanwhile no reason why not to stick with librium or valium if people want longer half lives.

Depending on half life, maybe, just maybe could see a role in detox facilities for XR to hasten discharge. Tomorrow take this dose. Next day, this dose, and final dose is this on this day.

But I'm not going to waste my time even reading about it to see if has any place/potential - because name brand / on patent / too expensive.

It's got a very narrow use case. Only for patients who have been taking a steady regimen of Ativan divided into three daily doses. You're supposed to switch over to regular Ativan to increase or decrease the dose. Only available in 1 mg, 2 mg, or 3 mg tablets.

-------------------------DOSAGE AND ADMINISTRATION----------------------
• Recommended dosage of LOREEV XR is equal to the total daily dose of lorazepam tablets (at the previous three times daily dosage) (2.1)
• Administer LOREEV XR orally once daily in the morning (2.2)
• Capsules may be swallowed whole or opened and the entire contents sprinkled onto applesauce. Do not crush or chew (2.2)
• For dosage adjustments, discontinue LOREEV XR and switch to lorazepam tablets to adjust dosage (2.3)

2.3 Dosage Increase for Inadequate Clinical Response
If the clinical response to LOREEV XR is inadequate and a dosage increase in needed, discontinue LOREEV XR and switch to lorazepam tablets to increase the dosage. If an adequate clinical response is achieved with a stable, evenly divided three times daily dosage of lorazepam tablets, resume LOREEV XR once daily dosing with the total daily dose of lorazepam tablets

 

[Sushirolls]

wow.

 

[aim-agm]

Only appropriate use case I can think of is a catatonia controlled with chronic benzo that responds to lorazepam but not other benzos.

 

[Sushirolls]

Only appropriate use case I can think of is a catatonia controlled with chronic benzo that responds to lorazepam but not other benzos.

They'll have a robust market right there! /sarcasm

Wondering what they thought their market would be.

The ability to put into apple sauce also a very tiny niche use...

 

[aim-agm]

They'll have a robust market right there! /sarcasm

Wondering what they thought their market would be.

The ability to put into apple sauce also a very tiny niche use...

I wonder if it was cheap enough to develop that they come out ahead just on inappropriate prescription is worth it.

 

[Sushirolls]

I wondered the same. But didn't feel the desire to actually type it out.
Or perhaps the ARNP population will Rx it.
I usually see the patients on the latest name brand drugs, as transfers from ARNPs.

 

[ObsequiousAplomb]

I wondered the same. But didn't feel the desire to actually type it out.
Or perhaps the ARNP population will Rx it.
I usually see the patients on the latest name brand drugs, as transfers from ARNPs.

nurses are so used to the free lunches at doctors offices that they don't seem to be swayed by the ethics of doling out fistfuls of whatever whoever brought them lunch. That may be biased by my experience of NPs and PAs eating up every word a drug rep has said while I'm in the room with them.

 

[shoomer]

nurses are so used to the free lunches at doctors offices that they don't seem to be swayed by the ethics of doling out fistfuls of whatever whoever brought them lunch. That may be biased by my experience of NPs and PAs eating up every word a drug rep has said while I'm in the room with them.

Honestly, physicians are also swayed by pharmaceutical marketing, otherwise they wouldn't do it. But midlevels definitely do not have the same background in terms of understanding the science and how pharma will present very skewed data to sell their products.

 

[psycho-matic]

I've used alprazolam ER 3 or 4 times over the years with certain patients. I didn't know there was an ativan xr.

 

[Merovinge]

Only appropriate use case I can think of is a catatonia controlled with chronic benzo that responds to lorazepam but not other benzos.

Do you even try other BZDs? I've always used Ativan first line for catatonia. Could easily see this being a nice option for outpatient catatonia management, which is to say the tiniest TAM ever, but would still be nice if it was covered in that place.