Berry aneurysms

[yoyohomieg5432]

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I don't really understand what is causing these. I know they are associated with ADPKD and ehlers danlos.. Does that mean you only see these if you have one of those conditions?

Does hypertertension cause these or not? I know HTN is associated with the charcot-bouchard aneurysms so I don't know if it also causes these. I haven't had much luck finding a concrete answer about this.

 

[ftp902]

My understanding is that HTN or any cause of HTN can cause BA because of intrinsic weakness of anterior/posterior communicating arteries that do not have smooth muscle in the media layer.

for other causes you mentioned, ADPKD increases renin release --> increased HTN --> BA. For EDS, I think it further weakens the artery and predisposing it to BA.

you will probably see BA in individuals with HTN or with coarctation who have HTN in upper extremities including carotid arteries.

 

[zhopv10]

^ that is what Goljan says, Uworld if I remember right also suggests that the actual gene product deficient in ADPKD contributes to the weakness so that could be a possibility but HTN is of course the main driving force I think as ftp902 said.


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