prognosis is a newer app family on iOS and Android that looks really popular. It has a cardio app that could replace the littmann one and looks like there are several others.
Prognosis won't replace Littmann; Prognosis is a more like a game; Littmann is a heart sounds practice app.
With prognosis, basically physicians send in stripped down case vignettes. The Prognosis team then builds them into the game and incorporates the ability to order tests and treatments for what you think might be going on based on the given history and physical exam. You get graded according to what you order.
There are 3 prognosis apps that I'm aware of. Prognosis. Prognosis Cardiology, and Prognosis Diabetes. They were fun first year, but now they're getting kinda boring.
So I'm on an iPhone5 atm, and here's my list of recommended apps:
Epocrates (and they have a whole suite of like 10 different apps) I downloaded them all and threw them in a folder on the phone so they're kept together, and I'd say that these are my most commonly used applications in clinical scenarios.
Mnemonics: I think it's like $1.99 but there are some handy memory tools in there for the stuff that just won't stay in the memory well.
MPR (Monthly Prescribing Reference), some redundancy with Epocrates, but there are some drugs in here that aren't in there, and vice-versa.
Eponyms: I use the "star" function to label the eponyms that come up in each block, that way I can go back and review them before exams.
Skyscape: This is a lot like Epocrates, but again, there are some nice features here that Epocrates doesn't have.
Lippincott: These guys publish a lot of textbooks that are commonly used in medical school. They have some good quiz apps, and they have an awesome app that every medical student with an iOS device should download immediately while it's still free. It's called Rubin's Pathology, and it's got about 2K flashcards that you'll really be glad to have when prepping for boards.
Littmann or Blaufuss soundbuilders
: These are for hearing abnormal heart sounds, just nice practice tools. They're not that close to the real thing, but they give you a good idea, and short of having a friend with a murmur or S3/S4 etc. this is about as good as you'll get on your own.
Doctor's In Training 5th Degree Pharm: It might cost a dollar or two, but I think it's worth it for the practice it will give you. Pharm can be a real bear sometimes, but this app can help. It's a matching game where you line up drug name, indication, side effects, MOA, etc.
Bento: I'm a Mac user, and I have Bento on my MBP. It's a customizable database software application that I use to store disease info, basically I'll have a file for each disease with data entry spots for pathology, physiology, histology, pharmacology, genetics, clinical presentation etc. Helps me tie everything together sometimes. I also have a pretty extensive microbiology data-base going. The app syncs with the software on the Mac, and lets you browse your databases on the go so it turns into a nice review tool when I'm riding the train or waiting in line at the grocery store etc.
I've got tons of others, but those are the big ones that I think are most worthwhile.