biochem/physio question

[helgs1727]

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Each of the following appears in the glomerular filtrate in concentrations approximately equal to those in plasma EXCEPT one. Which one is the exception?

a) Urea
b) Glucose
c) Amino acids
d) Steroid hormones
e) Plasma electrolytes

Answer according the 1998 answer key: d

i don't understand why this is answer, anyone want to help clear this up for me?

 

[porcelain258]

Steroid hormones are lipids and not soluble in plasma water.
Their transport in plasma is achieved by attachment of the hormone to a protein—a
binding globulin—that is miscible with water. Filtration at the kidney glomerulus involves
water and small molecules. Large molecules, such as the binding globulins and their
attached steroid hormones, are prevented from crossing the glomerular barrier to enter
the glomerular filtrate.
Urea (choice A), glucose (choice B), amino acids (choice C), and electrolytes (choice E)
are particles small enough to cross glomerular membranes and enter the filtrate

this was the explanation given in nbde part q version thread by indian graduate.....hope it'll help

 

[helgs1727]

thank you!!!