biochemistry question

[drkooks]

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in decks , uncompetitive inhibition is like non competitive inhibition except that it join to enzyme substrate complex...so according,km constant and v max decrease..
in mosby's km and vmax decrease
i am confused ...can someone help

 

[NYtimes]

in decks , uncompetitive inhibition is like non competitive inhibition except that it join to enzyme substrate complex...so according,km constant and v max decrease..
in mosby's km and vmax decrease
i am confused ...can someone help

uncompetitive inhibitors can be bind to ES only, but Non competitive inhibitor can be bind to both ES and E.b/c in Noncompetitive inhibition, S and I combine to the different sites of E.
Vmax will decrease in uncompetitive with any amounth of substrate.
in Noncompetitive inhibition, you can assume its a combination of compatitive and uncompetitive. if the I 's affinity to E is higher than S's affinity to E, the lines would be more like competitive lines, if the S 's affinity is higher to E, it would be close to uncompetitive inhibitor and the lines would be more parallel.

 

[NYtimes]

cortisol stimulates synthesis in the liver of?

• glucokinase
• PFK
• pyruvate carboxylase
• pyruvate kinase

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[BUSODM]

cortisol stimulates synthesis in the liver of?

• glucokinase
• PFK
• pyruvate carboxylase
• pyruvate kinase

I think it is glucokinase.correct me if I am wrong

 

[BUSODM]

cortisol stimulates synthesis in the liver of?

• glucokinase
• PFK
• pyruvate carboxylase
• pyruvate kinase

---------------------------------------------------------

cotisol stimulates Phosphenolpyruvate carboxykinase but there is no option for this .could anybody tell what is the answer,thanks

 

[Ride]

Cortisol stimulates gluconeogenesis. The only enzyme in the answer choices that participates in gluconeogenesis is pyruvate carboxlyase. All other choices (glucokinase, phosphofructokinase, and pyruvate kinase) are enzymes of glycolysis.
So, I'd say the answer was pyruvate carboxylase.

 

[BUSODM]

Cortisol stimulates gluconeogenesis. The only enzyme in the answer choices that participates in gluconeogenesis is pyruvate carboxlyase. All other choices (glucokinase, phosphofructokinase, and pyruvate kinase) are enzymes of glycolysis.
So, I'd say the answer was pyruvate carboxylase.

yeah only option would be pyruvate carboxylase