Biology Question

[RozhonDDS]

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Which is the intrcellular buffer of the body?

I can't determine if its PHOSPHATE or BICARBONATE

Does anyone know?

 

[lifeisgood]

Inter or intra-cellular?

 

[MaxL221]

Bicarbonate...i believe

 

[Resonance]

The phosphate system buffers the intracellular fluid of cells at physiological pH and the carbonate system is an important buffer system in blood plasma.

 

[RozhonDDS]

Inter or intra-cellular?

intra

 

[RozhonDDS]

so is it phosphate or bicarbonate

 

[MaxL221]

bicarbonate...positive for overall body

 

[Clover]

The phosphate system buffers the intracellular fluid of cells at physiological pH and the carbonate system is an important buffer system in blood plasma.

I think this is right.
For elevation of plasma H+ due to respiratory acidosis, the kidneys kick in and elevate plasma bicarbonate --> urine becomes acidic.


"Phosphates are important buffers intracellularly and in urine where their concentration is higher."
http://www.anaesthesiamcq.com/AcidBaseBook/ab2_2b.php

So in other words, to answer your question, between phosphate and bicarbonate, the intracellular buffering system is phosphate.

 

[Shane41]

Does anyone know if this is right? I thought it was bicarbonate also.

 

[DonExodus]

Extracellularly, its bicarbonate.
Intracellularly, its proteins.

PO4 plays a role, but not as large as either of these do.