biostatistics question from nbme

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arkroyal

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This was a question from one of the NBME tests and I was hoping someone could help me.

It was asking about allele frequencies for prostate cancer for allele B.

AA = 30
AB = 25
BB = 45

For some reason, these questions always stumble me. Thanks

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there are 60 As from AA (30 x 2)
there are 25 As from AB (25 x 1)

There are 25 Bs from AB (25 x1)
There are 90 Bs from BB (45 x 2)

So total there are 60+25+25+90 possible single alleles out there so 200

Frequency of A is 85/200

Frequency of B is 115/200
 
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