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biostatistics question from nbme

Discussion in 'Step I' started by arkroyal, Jun 14, 2008.

  1. arkroyal

    arkroyal Member
    7+ Year Member

    Dec 3, 2005
    Likes Received:
    This was a question from one of the NBME tests and I was hoping someone could help me.

    It was asking about allele frequencies for prostate cancer for allele B.

    AA = 30
    AB = 25
    BB = 45

    For some reason, these questions always stumble me. Thanks
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  3. Instatewaiter

    Instatewaiter But... there's a troponin
    10+ Year Member

    Apr 28, 2006
    Likes Received:
    Attending Physician
    there are 60 As from AA (30 x 2)
    there are 25 As from AB (25 x 1)

    There are 25 Bs from AB (25 x1)
    There are 90 Bs from BB (45 x 2)

    So total there are 60+25+25+90 possible single alleles out there so 200

    Frequency of A is 85/200

    Frequency of B is 115/200

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