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Here are many peer reviewed articles on Etomidate and Critically ill patients.
Critical Care 2006;10 (4) R105
Critical Care 2007 April 35 (4) 1012-8
Critical Care 2007 May 24; 11 (3); R61
Another good study:
Chest 2005 March; 127 (3) 707-09
It seems if you use Etomidate (even a single low dose) MANY authors are recommending coverage with steroids.
Chest 2006; 10 (4): R105
This study recommends a moratorium on etomidate use period.
The two CHEST journal articles state that etomidate without steroid supplementation will cause 1in 5 patients that got the drug to DIE as a result. Pretty strong wording and a 20% mortality due to etomidate use!
The bottom line is pretty clear: Use etomidate at your own peril and if you use it at all YOU MUST GIVE STEROIDS for several days or more.
Blade
Mil,
I got the data on Etomidate. Here are the studies. I also stated my conclusion DAYS AGO.
Blade