Blood Transfusion Question

[DrVanNostran]

What is the most common pathogen transmitted by Transfusion?
RR Path, page 267=CMV
FA 2009, page 502=Hep C
Goljan audio-->I think he says Hep C? But that was in '04 or so

In RR, the explanation for CMV seems correct. I can't remember what we learned throughout the school year. Does anyone have a definitive answer on this, or did Uworld give an answer?

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[hartbot]

I thought Goljan said Hep B is most common infection, but CMV is most common antibody present

 

[otacon88]

Goljan audio says Hep B because the viral load is like 10 times greater than any other disease.

but it seems like CMV would be the correct answer - i have read this in some other medical textbook also, can't remember which one

 

[orc]

We learned Hep B in class.

 

[African]

I believe it is cytomegalovirus but could it be different from country to country?

 

[DrTacoElf]

As of 2006, the risk of acquiring hepatitis B via blood transfusion in the United States is about 1 in 250,000 units transfused, and the risk of acquiring HIV or hepatitis C in the U.S. via a blood transfusion is estimated at 1 in 2,000,000 (2 million) units transfused


But CMV is intracellular so its likely also....

 

[liability]

I think y'all are mixing up infection via transfusion with an accidental needlestick.

Transfusion: CMV
Needlestick from a rando: HBV

 

[TooMuchResearch]

I think y'all are mixing up infection via transfusion with an accidental needlestick.

Transfusion: CMV
Needlestick from a rando: HBV

They probably figured it out by now. Or no longer care. Or are dead. It's an old thread.

 

[Phloston]

I think y'all are mixing up infection via transfusion with an accidental needlestick.

Transfusion: CMV
Needlestick from a rando: HBV

Is CMV really the most common transfused pathogen? That sounds a little strange because that seems difficult to prove. Most people who are immuno-competent just develop cold-like Sx if they develop Sx at all, so there would be no way to really accurately gauge CMV infection rates, I'd believe. I thought CMV infection was mainly just associated with organ transplantation, based on the cyclosporine the patient is on pre- and post-operatively.

As far as needle sticks are concerned, the chances of contracting the disease if stuck: HepB (~30-40%), HepC (~10-15%), HIV (~0.30-0.45%). That's just based on what I recall from Kaplan QBook.