Step I BMPR2

[faisal 2000]

hi
what is the function of bone morphogenetic protein receptor type 2 ?? and how does it cause PH?

 

[ChessMaster3000]

hi
what is the function of bone morphogenetic protein receptor type 2 ?? and how does it cause PH?

bmpr2 normally functions to regular growth of vascular smooth muscle particular in pulmonary vasculature. as a result, a defect in this would predispose to PPH. that should be all you need to know--I dont know if this is autosomal dominant or recessive however

edit--I changed it from vascular endthelium to vascular smooth muscle after consulting FA. My bad