BR lipids chapter

[deleted647690]

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There is a reaction shown in BR organic that shows vitamin A (retinol) because oxidized to retinal using NADH (a reducing agent). Is this incorrect? How can a reducing agent (which gets oxidized) cause oxidation of another compound?

 

[aldol16]

Do you have a screenshot or something with the actual reaction? Sometimes, the redox pair NADH and NAD+ are used interchangeably, although they should not be to be chemically precise. So retinol is oxidized by retinol dehydrogenase, which uses the NAD+ cofactor to perform the oxidation.

 

[krf710]

I was wondering the same thing! I just covered this chapter yesterday and it confused me as well. Also, it kind of contradicts the last page of the chapter summary where it lists what agents oxidize and reduce. I don't have the book in front of me today so I can't provide a screenshot 🙁

 

[deleted647690]

.

 

[deleted647690]

Do you have a screenshot or something with the actual reaction? Sometimes, the redox pair NADH and NAD+ are used interchangeably, although they should not be to be chemically precise. So retinol is oxidized by retinol dehydrogenase, which uses the NAD+ cofactor to perform the oxidation.

Sorry, I should have rotated it

 

[Pono_0001]

yup. here's the correct graph

http://www.chemgapedia.de/vsengine/...in_a/stoffwechsel/grafiken/retinol_ox.svg.jpg