Poppycock!Genetics is dumb. The more you know, the more you feel overwhelmed. It really makes me wonder how well pharmacogenentics and pharmacogenomics will be integrated into medicine as you really have to understand genetics to accurately utilize the info imo. This rules out most physcians (and pharmacists over 30). Better therapy or not, if they don't get behind it, it might be another few generations before it become common practice.
One would think, but things like x-inactivation, pharmacogenomics (genome wide comparisons), epigenetics, and metagenomes (lymph cells) make it a little more complicated than if x then y in the case of pharmacogenetics. my 0.02Poppycock!
the goal is to develop simple clinical tests that indicate the presence of the slow or fast metabolizer allele. You don't have to understand the theory; just read the test result.
We already have these for some 'high adverse reaction risk' drugs. All acute lymphoblastic leukemia patients are screened before treatment with 6-mercaptopurine.
But, I agree genetics sometimes seems convoluted.