I agree that December and January are definitely the heaviest interview months for most people. However, if you can take an elective with a lighter schedule/more time to get away in November, you can actually front-load your schedule knock out quite a few interviews during this month. I actually had 6 interviews done by Thanksgiving, and I was on a rotation at the time. I ended up only having to take a couple of days off because the interviews were either 1) at or near my home institution, 2) a 2-hour drive away, or 3) scheduled for dates when I was not working. Also, I worked it out with my attending and fellows so that I could make up any days I missed by covering a weekend or taking an extra call. It ended up being no big deal and, while November was busy, it was very productive. I thought it was well worth it to get so many interviews out of the way so early.
If you can do the ones closest to home first, then you'll need to take of less time to travel - thus, you can do them while you're on a rotation (most are good about letting you have a day off here or there). This way, you can save your month(s) off to travel to the programs that demand long car rides or plane trips.