Realistically, no.
However when someone has a glut of middle author papers, I'm more likely to probe the details when interviewing. I do know that for many, the volume is impressive. But when I'm ranking people, I'm much more interested in quality. It's always great when an applicant can describe a project they took from beginning to end (especially if they helped develop the original question).
Also, if there are a bunch of abstracts with no manuscripts, I'm going to ask a question about "why". Not because I think it's a disqualifier, but because the answer can be informative.